Oncology Board Exam Started: Jul 13, 2026 02:34 Page 10 of 53 Attempt #1702 Overall: 0 / 264 questions answered Question 46 / 264 Not answered At a preventive-care consultation: A patient with colon cancer has mismatch repair deficiency. Why is this clinically important? A. It proves benign disease B. It eliminates need for staging C. It means antibiotics cure cancer D. It is unrelated to family risk E. It may suggest Lynch syndrome and guide immunotherapy decisions Show Answer & Explanation Correct Answer: E Explanation: [Oncology] Mismatch repair deficiency can indicate Lynch syndrome and predicts benefit from immune checkpoint inhibitors in selected disease. Reference: NCCN Colon Cancer and Genetic/Familial High-Risk Assessment Guidelines. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 47 / 264 Not answered At a primary-care follow-up visit: A man with metastatic prostate cancer has bone pain and very high PSA. What systemic therapy is foundational? A. Antibiotics only B. Colonoscopy C. Androgen deprivation therapy D. Thyroxine E. Aspirin monotherapy Show Answer & Explanation Correct Answer: C Explanation: [Oncology] Androgen deprivation is foundational systemic therapy for advanced prostate cancer. Reference: EAU/NCCN Prostate Cancer Guidelines. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 48 / 264 Not answered At a primary-care follow-up visit: A patient receiving chemotherapy develops fever 38.5 C and neutrophils 0.3 x10^9/L. What is the immediate management? A. Wait for culture results before antibiotics B. Oral antihistamine only C. No treatment if BP is normal D. Prompt empiric broad-spectrum anti-pseudomonal antibiotics E. Live vaccine Show Answer & Explanation Correct Answer: D Explanation: [Oncology] Febrile neutropenia is an oncologic emergency requiring immediate empiric broad-spectrum antibiotics. Reference: IDSA Fever and Neutropenia Guideline. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 49 / 264 Not answered At a preventive-care consultation: A 55-year-old woman has a suspicious breast mass and abnormal mammogram. What is required for diagnosis before definitive cancer treatment? A. Core needle biopsy B. CA 15-3 alone C. Empirical mastectomy without tissue D. Repeat mammogram in 5 years E. Antibiotics only for all masses Show Answer & Explanation Correct Answer: A Explanation: [Oncology] Breast cancer diagnosis requires tissue confirmation, commonly by core needle biopsy. Reference: NCCN Breast Cancer Guidelines. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 50 / 264 Not answered During preoperative assessment: A patient with colon cancer has mismatch repair deficiency. Why is this clinically important? A. It proves benign disease B. It eliminates need for staging C. It means antibiotics cure cancer D. It is unrelated to family risk E. It may suggest Lynch syndrome and guide immunotherapy decisions Show Answer & Explanation Correct Answer: E Explanation: [Oncology] Mismatch repair deficiency can indicate Lynch syndrome and predicts benefit from immune checkpoint inhibitors in selected disease. Reference: NCCN Colon Cancer and Genetic/Familial High-Risk Assessment Guidelines. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 10 of 53 Next → »