Oncology Board Exam Started: Jul 12, 2026 19:30 Page 53 of 53 Attempt #776 Overall: 0 / 264 questions answered Question 261 / 264 Not answered In an outpatient specialty clinic: a 45-year-old man presents with fever during cytotoxic therapy. Relevant risk context includes smoking. What is the most likely diagnosis? A. Febrile neutropenia B. Breast cancer recurrence concern C. Lung carcinoma suspicion D. Malignant hypercalcemia E. Spinal cord compression syndrome Show Answer & Explanation Correct Answer: C Explanation: The pattern of fever during cytotoxic therapy with risk factors such as smoking is most consistent with Lung carcinoma suspicion. This answer best matches the expected diagnostic framework for Oncology. Reference: NCCN Clinical Practice Guidelines in Oncology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 262 / 264 Not answered During morning rounds: a 64-year-old man is evaluated for fever during cytotoxic therapy in the context of immobility. Which is the most appropriate next investigation? A. CBC with differential B. MRI for suspected cord compression C. Tissue biopsy for histologic confirmation D. Serum calcium with ECG E. Staging CT or PET pathway Show Answer & Explanation Correct Answer: E Explanation: Staging CT or PET pathway is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: ESMO Clinical Practice Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 263 / 264 Not answered During a primary-care follow-up visit: a 48-year-old woman presents with back pain with motor deficit. Relevant risk context includes advanced-stage disease. What is the most likely diagnosis? A. Malignant hypercalcemia B. Spinal cord compression syndrome C. Lung carcinoma suspicion D. Cancer-associated thrombosis E. Febrile neutropenia Show Answer & Explanation Correct Answer: B Explanation: The pattern of back pain with motor deficit with risk factors such as advanced-stage disease is most consistent with Spinal cord compression syndrome. This answer best matches the expected diagnostic framework for Oncology. Reference: ASCO Guidelines; Oncology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 264 / 264 Not answered During a primary-care follow-up visit: a 81-year-old woman is evaluated for confusion with severe hypercalcemia in the context of smoking. Which is the most appropriate next investigation? A. Serum calcium with ECG B. MRI for suspected cord compression C. Duplex imaging for suspected thrombosis D. CBC with differential E. Staging CT or PET pathway Show Answer & Explanation Correct Answer: B Explanation: MRI for suspected cord compression is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: ASCO Guidelines; Oncology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 53 of 53 Submit Exam