Oncology Board Exam Started: Jul 13, 2026 07:21 Page 13 of 53 Attempt #2302 Overall: 0 / 264 questions answered Question 61 / 264 Not answered A 50-year-old female has an ER+ PR+ HER2- breast cancer. Most appropriate endocrine therapy: A. Tamoxifen only B. Aromatase inhibitors C. Trastuzumab D. Chemotherapy alone E. Radiation therapy Show Answer & Explanation Correct Answer: B Explanation: Aromatase inhibitors are preferred for postmenopausal women with HR+ breast cancer due to better efficacy than tamoxifen. Reference: National Comprehensive Cancer Network Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 62 / 264 Not answered At a multidisciplinary case conference: a 71-year-old woman is evaluated for confusion with severe hypercalcemia in the context of advanced-stage disease. Which is the most appropriate next investigation? A. CBC with differential B. Tissue biopsy for histologic confirmation C. MRI for suspected cord compression D. Staging CT or PET pathway E. Serum calcium with ECG Show Answer & Explanation Correct Answer: C Explanation: MRI for suspected cord compression is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: ESMO Clinical Practice Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 63 / 264 Not answered During ward handover: a 54-year-old man is evaluated for back pain with motor deficit in the context of smoking. Which is the most appropriate next investigation? A. MRI for suspected cord compression B. Staging CT or PET pathway C. CBC with differential D. Serum calcium with ECG E. Tissue biopsy for histologic confirmation Show Answer & Explanation Correct Answer: A Explanation: MRI for suspected cord compression is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: ASCO Guidelines; Oncology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 64 / 264 Not answered A 65-year-old with smoking history has a 3 cm lung nodule and clinical stage IIIA NSCLC. Most appropriate treatment: A. Observation B. Chemotherapy alone C. Surgical resection D. Concurrent chemoradiation E. Palliative care Show Answer & Explanation Correct Answer: C Explanation: Surgical resection is the best treatment option for stage IIIA NSCLC when the patient is fit for surgery. Reference: American Society of Clinical Oncology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 65 / 264 Not answered During a primary-care follow-up visit: a 32-year-old woman presents with confusion with severe hypercalcemia. Relevant risk context includes advanced-stage disease. What is the most likely diagnosis? A. Lung carcinoma suspicion B. Cancer-associated thrombosis C. Febrile neutropenia D. Breast cancer recurrence concern E. Malignant hypercalcemia Show Answer & Explanation Correct Answer: E Explanation: The pattern of confusion with severe hypercalcemia with risk factors such as advanced-stage disease is most consistent with Malignant hypercalcemia. This answer best matches the expected diagnostic framework for Oncology. Reference: NCCN Clinical Practice Guidelines in Oncology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 13 of 53 Next → »