Oncology Board Exam Started: Jul 13, 2026 05:19 Page 44 of 53 Attempt #2079 Overall: 0 / 264 questions answered Question 216 / 264 Not answered During ward handover: a 64-year-old man presents with new mass with constitutional symptoms. Relevant risk context includes immobility. What is the most likely diagnosis? A. Malignant hypercalcemia B. Cancer-associated thrombosis C. Spinal cord compression syndrome D. Breast cancer recurrence concern E. Febrile neutropenia Show Answer & Explanation Correct Answer: C Explanation: The pattern of new mass with constitutional symptoms with risk factors such as immobility is most consistent with Spinal cord compression syndrome. This answer best matches the expected diagnostic framework for Oncology. Reference: ASCO Guidelines; Oncology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 217 / 264 Not answered During morning rounds: a 25-year-old man has progressive weight loss with chronic cough with risk profile of advanced-stage disease. After initial stabilization and assessment, what is the most appropriate management step? A. Early palliative symptom control integration B. Dexamethasone with urgent oncologic referral for cord compression C. Guideline-based systemic therapy selection D. Urgent broad-spectrum antibiotics in febrile neutropenia E. Bisphosphonate-based hypercalcemia management Show Answer & Explanation Correct Answer: E Explanation: Bisphosphonate-based hypercalcemia management is preferred because it aligns with guideline-based care priorities, reduces avoidable complications, and supports safe outcomes in Oncology. Reference: NCCN Clinical Practice Guidelines in Oncology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 218 / 264 Not answered At a multidisciplinary case conference: a 71-year-old woman is evaluated for unilateral leg swelling in active cancer in the context of high tumor burden. Which is the most appropriate next investigation? A. Tissue biopsy for histologic confirmation B. MRI for suspected cord compression C. Serum calcium with ECG D. Staging CT or PET pathway E. CBC with differential Show Answer & Explanation Correct Answer: D Explanation: Staging CT or PET pathway is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: ASCO Guidelines; Oncology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 219 / 264 Not answered In an emergency department assessment: a 39-year-old man is evaluated for progressive weight loss with chronic cough in the context of recent chemotherapy. Which is the most appropriate next investigation? A. Serum calcium with ECG B. MRI for suspected cord compression C. Staging CT or PET pathway D. CBC with differential E. Tissue biopsy for histologic confirmation Show Answer & Explanation Correct Answer: A Explanation: Serum calcium with ECG is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: WHO Classification and Guidance Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 220 / 264 Not answered At a multidisciplinary case conference: a 63-year-old man is evaluated for progressive weight loss with chronic cough in the context of recent chemotherapy. Which is the most appropriate next investigation? A. Duplex imaging for suspected thrombosis B. Tissue biopsy for histologic confirmation C. Serum calcium with ECG D. MRI for suspected cord compression E. CBC with differential Show Answer & Explanation Correct Answer: B Explanation: Tissue biopsy for histologic confirmation is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Oncology. Reference: NCCN Clinical Practice Guidelines in Oncology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 44 of 53 Next → »