Neurology Board Exam Started: Jul 13, 2026 08:15 Page 45 of 57 Attempt #2369 Overall: 0 / 284 questions answered Question 221 / 284 Not answered During a primary-care follow-up visit: a 26-year-old man is evaluated for optic neuritis with sensory deficits in the context of hypertension. Which is the most appropriate next investigation? A. Autoantibody panel for neuromuscular disease B. Lumbar puncture when indicated C. MRI brain with diffusion D. Non-contrast CT brain E. CT angiography head and neck Show Answer & Explanation Correct Answer: B Explanation: Lumbar puncture when indicated is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Neurology. Reference: AHA/ASA Stroke Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 222 / 284 Not answered During a primary-care follow-up visit: a 59-year-old woman is evaluated for thunderclap headache in the context of hypertension. Which is the most appropriate next investigation? A. Autoantibody panel for neuromuscular disease B. EEG C. MRI brain with diffusion D. Non-contrast CT brain E. Lumbar puncture when indicated Show Answer & Explanation Correct Answer: E Explanation: Lumbar puncture when indicated is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Neurology. Reference: ILAE Epilepsy Guidance; Neurology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 223 / 284 Not answered At a multidisciplinary case conference: a 80-year-old woman presents with recurrent pulsatile headache with photophobia. Relevant risk context includes autoimmune background. What is the most likely diagnosis? A. Myasthenia gravis B. Acute ischemic stroke C. Migraine with aura D. Multiple sclerosis E. Subarachnoid hemorrhage Show Answer & Explanation Correct Answer: A Explanation: The pattern of recurrent pulsatile headache with photophobia with risk factors such as autoimmune background is most consistent with Myasthenia gravis. This answer best matches the expected diagnostic framework for Neurology. Reference: McDonald Criteria for Multiple Sclerosis Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 224 / 284 Not answered At a multidisciplinary case conference: a 36-year-old man presents with thunderclap headache. Relevant risk context includes family history of epilepsy. What is the most likely diagnosis? A. Myasthenia gravis B. Migraine with aura C. Acute ischemic stroke D. Multiple sclerosis E. Subarachnoid hemorrhage Show Answer & Explanation Correct Answer: B Explanation: The pattern of thunderclap headache with risk factors such as family history of epilepsy is most consistent with Migraine with aura. This answer best matches the expected diagnostic framework for Neurology. Reference: AAN Practice Guidelines; Neurology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 225 / 284 Not answered In an outpatient specialty clinic: a 82-year-old woman presents with sudden unilateral weakness and aphasia. Relevant risk context includes smoking. What is the most likely diagnosis? A. Myasthenia gravis B. Focal epilepsy C. Subarachnoid hemorrhage D. Multiple sclerosis E. Acute ischemic stroke Show Answer & Explanation Correct Answer: B Explanation: The pattern of sudden unilateral weakness and aphasia with risk factors such as smoking is most consistent with Focal epilepsy. This answer best matches the expected diagnostic framework for Neurology. Reference: AAN Practice Guidelines; Neurology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 45 of 57 Next → »