Endocrinology Board Exam Started: Jul 13, 2026 03:29 Page 50 of 57 Attempt #1841 Overall: 0 / 283 questions answered Question 246 / 283 Not answered In an emergency department assessment: a 76-year-old woman presents with renal stones with hypercalcemia. Relevant risk context includes postpartum thyroid risk. What is the most likely diagnosis? A. Cushing syndrome B. Type 2 diabetes mellitus C. Primary adrenal insufficiency D. Graves disease E. Primary hypothyroidism Show Answer & Explanation Correct Answer: D Explanation: The pattern of renal stones with hypercalcemia with risk factors such as postpartum thyroid risk is most consistent with Graves disease. This answer best matches the expected diagnostic framework for Endocrinology. Reference: American Thyroid Association Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 247 / 283 Not answered During ward handover: a 29-year-old man is evaluated for proximal myopathy with striae in the context of postpartum thyroid risk. Which is the most appropriate next investigation? A. Morning cortisol with ACTH B. Pituitary MRI when indicated C. Overnight dexamethasone suppression test D. HbA1c with fasting glucose E. TSH with free T4 Show Answer & Explanation Correct Answer: A Explanation: Morning cortisol with ACTH is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Endocrinology. Reference: ADA Standards of Care in Diabetes Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 248 / 283 Not answered At a preventive-care consultation: a 58-year-old man is evaluated for proximal myopathy with striae in the context of pituitary pathology. Which is the most appropriate next investigation? A. Serum calcium and PTH B. TSH with free T4 C. Pituitary MRI when indicated D. HbA1c with fasting glucose E. Morning cortisol with ACTH Show Answer & Explanation Correct Answer: A Explanation: Serum calcium and PTH is the most appropriate next test because it directly clarifies the leading diagnosis and guides immediate management in Endocrinology. Reference: Endocrine Society Clinical Practice Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 249 / 283 Not answered At a preventive-care consultation: a 63-year-old man presents with renal stones with hypercalcemia. Relevant risk context includes pituitary pathology. What is the most likely diagnosis? A. Primary adrenal insufficiency B. Primary hypothyroidism C. Graves disease D. Cushing syndrome E. Type 2 diabetes mellitus Show Answer & Explanation Correct Answer: D Explanation: The pattern of renal stones with hypercalcemia with risk factors such as pituitary pathology is most consistent with Cushing syndrome. This answer best matches the expected diagnostic framework for Endocrinology. Reference: Endocrine Society Clinical Practice Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 250 / 283 Not answered In an outpatient specialty clinic: a 48-year-old woman has fatigue with cold intolerance with risk profile of autoimmune disease. After initial stabilization and assessment, what is the most appropriate management step? A. Levothyroxine replacement with TSH-guided titration B. Antithyroid therapy with risk stratification C. Evidence-based osteoporosis risk reduction D. Targeted management of hypercortisolism cause E. Urgent stress-dose corticosteroid in adrenal crisis Show Answer & Explanation Correct Answer: E Explanation: Urgent stress-dose corticosteroid in adrenal crisis is preferred because it aligns with guideline-based care priorities, reduces avoidable complications, and supports safe outcomes in Endocrinology. Reference: AACE Endocrine Guidance; Endocrinology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 50 of 57 Next → »