Rheumatology Board Exam Started: Jul 13, 2026 07:14 Page 13 of 53 Attempt #2277 Overall: 0 / 263 questions answered Question 61 / 263 Not answered A 45-year-old female with 8 weeks of symmetric polyarthritis affecting hands and feet has elevated RF and anti-CCP antibodies. Most appropriate therapy: A. NSAIDs alone B. Corticosteroids monotherapy C. DMARDs such as methotrexate D. Physical therapy alone E. Biologics without conventional DMARDs Show Answer & Explanation Correct Answer: C Explanation: DMARDs such as methotrexate are the gold standard for early RA and should be started early to prevent joint damage. Reference: American College of Rheumatology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 62 / 263 Not answered In an emergency department assessment: a 42-year-old man presents with inflammatory back pain improving with exercise. Relevant risk context includes hyperuricemia. What is the most likely diagnosis? A. Rheumatoid arthritis B. Dermatomyositis C. Giant cell arteritis D. Axial spondyloarthritis E. Acute gout flare Show Answer & Explanation Correct Answer: D Explanation: The pattern of inflammatory back pain improving with exercise with risk factors such as hyperuricemia is most consistent with Axial spondyloarthritis. This answer best matches the expected diagnostic framework for Rheumatology. Reference: EULAR Recommendations; Rheumatology topic-specific current guideline update Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 63 / 263 Not answered A 25-year-old female with SLE presents with fever rash and arthralgia. Lab shows low complement levels and elevated anti-dsDNA. Most appropriate therapy: A. Observation only B. NSAIDs C. Hydroxychloroquine and low-dose corticosteroids D. Immunosuppression with cyclophosphamide E. Plasmapheresis Show Answer & Explanation Correct Answer: C Explanation: Hydroxychloroquine plus low-dose corticosteroids is appropriate for mild to moderate SLE manifestations. Reference: American College of Rheumatology Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 64 / 263 Not answered During a primary-care follow-up visit: a 39-year-old woman presents with new headache with jaw claudication. Relevant risk context includes recent steroid taper. What is the most likely diagnosis? A. Giant cell arteritis B. Systemic lupus erythematosus flare C. Rheumatoid arthritis D. Dermatomyositis E. Axial spondyloarthritis Show Answer & Explanation Correct Answer: D Explanation: The pattern of new headache with jaw claudication with risk factors such as recent steroid taper is most consistent with Dermatomyositis. This answer best matches the expected diagnostic framework for Rheumatology. Reference: ACR Rheumatology Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 65 / 263 Not answered At a preventive-care consultation: a 67-year-old man has first MTP acute inflammation with risk profile of older age. After initial stabilization and assessment, what is the most appropriate management step? A. Biologic therapy escalation when indicated B. Urgent glucocorticoid for suspected giant cell arteritis C. Acute gout anti-inflammatory treatment D. Methotrexate-based DMARD initiation E. Multidisciplinary rehabilitation Show Answer & Explanation Correct Answer: A Explanation: Biologic therapy escalation when indicated is preferred because it aligns with guideline-based care priorities, reduces avoidable complications, and supports safe outcomes in Rheumatology. Reference: ACR Rheumatology Guidelines Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 13 of 53 Next → »