Hematology Board Exam Started: Jul 12, 2026 23:41 Page 5 of 53 Attempt #1357 Overall: 0 / 262 questions answered Question 21 / 262 Not answered Question 55: At a primary-care follow-up visit: A patient has prolonged aPTT corrected by mixing study and low factor VIII. What is the diagnosis? A. Hemophilia B B. Warfarin excess C. Vitamin K deficiency only D. DIC E. Hemophilia A Show Answer & Explanation Correct Answer: E Explanation: [Hematology] Low factor VIII with correction on mixing supports factor VIII deficiency, hemophilia A. Reference: WFH Guidelines for the Management of Hemophilia. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 22 / 262 Not answered Question 54: At a primary-care follow-up visit: A 70-year-old has anemia, renal impairment, hypercalcemia, and lytic bone lesions. What is the likely diagnosis? A. Chronic lymphocytic leukemia only B. Iron deficiency C. Hemophilia A D. Multiple myeloma E. Polycythemia vera Show Answer & Explanation Correct Answer: D Explanation: [Hematology] CRAB features with lytic lesions suggest symptomatic multiple myeloma. Reference: International Myeloma Working Group Criteria. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 23 / 262 Not answered Question 53: At a primary-care follow-up visit: A child has sickle cell disease, fever, chest pain, hypoxia, and new pulmonary infiltrate. What is the diagnosis? A. Simple vaso-occlusive pain only B. Asthma only C. Acute chest syndrome D. Pulmonary embolism proven E. Pneumothorax only Show Answer & Explanation Correct Answer: C Explanation: [Hematology] New infiltrate plus respiratory symptoms or hypoxia in sickle cell disease defines acute chest syndrome. Reference: NHLBI Sickle Cell Disease Expert Panel Report. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 24 / 262 Not answered Question 52: At a primary-care follow-up visit: A patient on unfractionated heparin develops platelet fall >50% on day 7 with new thrombosis. What is the likely diagnosis? A. Immune thrombocytopenia unrelated to heparin B. Heparin-induced thrombocytopenia C. DIC excluded D. TTP always E. Drug allergy without thrombosis Show Answer & Explanation Correct Answer: B Explanation: [Hematology] Timing, platelet fall, and thrombosis after heparin suggest HIT; stop heparin and use non-heparin anticoagulation. Reference: ASH Heparin-Induced Thrombocytopenia Guideline. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Question 25 / 262 Not answered Question 51: At a primary-care follow-up visit: A 23-year-old woman has microcytic anemia, ferritin 8 ng/mL, and heavy menses. What is the diagnosis? A. Iron deficiency anemia B. Thalassemia major proven C. Anemia of CKD only D. B12 deficiency E. Aplastic anemia Show Answer & Explanation Correct Answer: A Explanation: [Hematology] Low ferritin with microcytosis is diagnostic of iron deficiency anemia in the right context. Reference: British Society of Gastroenterology Iron Deficiency Anaemia Guideline. Reference: Comments & Discussion No comments yet. Be the first to comment! Your Name * Your Comment * (Max 200 chars) 200 characters remaining Post Comment Comments remaining this hour: 10/10 Cancel « ← Previous Page 5 of 53 Next → »